CMC Microsystems
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Joshua Hayes

Graduate Student

McGill University

Joshua graduated from Concordia University with a degree in Mechanical Engineering and pursued graduate studies at McGill University in the department of Experimental Medicine. His research focuses on the development and validation of the point of care plasmonic qPCR machine. Passionate about multidisciplinary research and improving public health, Joshua is continuing his work on adapting diagnostic techniques to the point of care with the goal of facilitating and improving patient care.

mcgill.ca

Sessions Joshua Hayes is a part of

Wednesday, June 8, 2022

What will it take to make personalized and precision medicine mainstream within 15 years?

3:50 pm to 5:05 pm
in Salon 9

Talk Description

Clinical Applications and Validation of the Point of Care Plasmonic PCR

The point of care (POC) plasmonic qPCR machine is a reinvention of the classical DNA amplification technique to be used at the point of care. It is ultra-rapid in nature and uses laser-excited gold nanoparticles as nano heaters to instantaneously heat samples from within the reaction mixture. The implementation of small vertical cavity surface emitting lasers (VCSELs) allows for the machine to be light, portable, and multi-channel. The machine supplies real time quantitative amplification data, resulting in efficient test-to-result turnover times. This presentation will discuss the prototype's functionality, thermal cycling performance, amplification performance (limit of detection, limit of quantitation, PCR efficiency), clinical viability, and potential as a competitive point of care device.

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