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Emmanuel Ho

Professor

University of Waterloo

Dr. Emmanuel Ho is currently an Associate Professor in the School of Pharmacy at the University of Waterloo and the theme lead for the Therapeutics & Theranostics section of the Waterloo Institute for Nanotechnology. His current research program is focused on the development and characterization of innovative nanomedicines, medical devices and biomaterials for imaging, treatment, and prevention of diseases including HIV/AIDS, cancer, and chronic wounds. Dr. Ho is the past President of the Canadian Chapter of the Controlled Release Society, the past Treasurer of the Canadian Society for Pharmaceutical Sciences (CSPS) and is currently an Associate Editor for Drug Delivery and Translational Research and the Journal of Pharmacy & Pharmaceutical Sciences. He was awarded the 2021 Leslie Dan Faculty of Pharmacy Leadership in Pharmaceutical Sciences Award, 2015 Association of Faculties of Pharmacy of Canada New Investigator Research Award and the 2014 GlaxoSmithKline / CSPS Early Career Award.

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Sessions Emmanuel Ho is a part of

Thursday, June 9, 2022

What does the future of advanced manufacturing look like?

3:50 pm to 5:05 pm

in Salon 11

Talk Description

3D Printing of Personalized Vaginal Implants For Controlled Tunable Drug Release

Customized, patient-specific implants are desirable for improved acceptability and therapeutic outcomes. Unfortunately, conventional methods of manufacturing can be costly and may take several weeks for fabrication. We designed and engineered novel intravaginal ring (IVR) medical devices via fused deposition modeling (FDM) three-dimensional (3D) printing for controlled delivery of hydroxychloroquine, IgG, gp120 fragment (encompassing the CD4 binding site), and coumarin-6 poly(lactic-co-glycolic acid)-polyethylene glycol (PLGA-PEG) nanoparticles (C6NP). Hydrophilic polyurethanes were utilized to 3D-print reservoir-type IVRs containing a tunable release controlling membrane with varying thickness and adaptable micro porous structures for controlled sustained drug delivery over 14 days.

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