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Kevin Moore

PhD Student

Western University

Kevin is entering his third year of the Medical Biophysics program at Western University. His research involves recapitulating vascular shear patterns over endothelial cells in microfluidics. He is a recent graduate of the Health Sciences program at the University of Ottawa.

schulich.uwo.ca

Sessions Kevin Moore is a part of

Thursday, June 9, 2022

What does the future of advanced manufacturing look like?

2:00 pm to 3:30 pm

in Salon 11

Talk Description

Assessing Endothelial Cell Mechanosensory Response to Multi-directional Wall Shear Stress in Microfludics

Early deposition of atherosclerotic plaque has been shown to develop preferentially in regions of the vasculature characterized by disturbed flow. The early mechanosensory actions of endothelial cells in these regions remain poorly understood. A microfluidic device capable of recapitulating disturbed flow over an endothelial monolayer has been developed. With this device, multi-directional flow can be passed over endothelial cells and their responses imaged over time. The results of this project indicate different mechanosensory responses of endothelial cells dependant on the flow patterns.

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